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V. A. Navale ¹, S. S. Mokle ¹, Archana Y. Vibhute ¹, K. G. Karamunge ¹, S. V. Khansole ¹, S. B. Junne ¹, Y. B. Vibhute ¹

Affiliations
1 P.G. Department of Chemistry, Yeshwant Mahavidyalaya, Nanded-431602 (M.S.), IN

Abstract

The synthesis of heterocyclic compounds containing flavones (4a-i) and 1,5-benzothiazepines (5a-i) from chalcone derivatives containing 3,4-methylenedioxy phenyl ring using microwave irradiation in 80-97% yield within 2-4 min. The work-up is simple, shorter reaction time, increase in reaction rate with better yields. The structures of synthetic compounds have been characterized using IR and ¹H NMR spectral data together with halogen analysis. All synthesized compounds have been screened for their antibacterial activity.

Keywords

Chalcones, Flavones, 1,5-Benzothiazepines, Microwave Irradiation, Antibacterial Activity.

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